Mark Bachman (mbachman@uci.edu)
Associate Director of Integrated Nanosystems Research Facility; Biomedical Engineering; Electrical Engineering
Development of new micromachining and integration techniques for metals and polymers, integration methods for optics and fluidics, and a variety of microdevices and micro/nano systems with applications in wireless, optical telecom, fluidics, medicine and biotechnology.
Bruce Blumberg (blumberg@uci.edu)
Developmental & Cell Biology
Gene regulation and intercellular signaling during embryonic development. Specifically,regulatory proteins called nuclear hormone receptors and their ligands
James Brody (jpbrody@uci.edu)
Biomedical Engineering
Application of surface plasmon resonance based sensors to quantifying DNA/protein interactions, studies of single proteases and 20 S proteasomes in vitro, and molecular biology and biochemical analysis of a module of genes expressed in breast cancers
Peter Burke (pburke@uci.edu)
Biomedical Engineering; Electrical Engineering
Development of high-speed semiconductors and high-frequency electronic and optical devices; Carbon Nanotubes
Zhongping Chen (z2chen@uci.edu)
Biomedical Engineering
Investigating light/tissue interactions; Developing medical diagnostic and therapeutic devices and instruments using advanced optical, microfabrication and biomedical technologies; Applications of these technologies for the early diagnosis of cancer and other diseases.
Ken Cho (kwcho@uci.edu)
Developmental & Cell Biology
Stem cell research and diabetes, Bioinformatics and functional genomics, Veterbrate embryology and growth factor signaling
Phil Collins (collinsp@uci.edu)
Physics
Electronic properties of devices and circuits made with novel, nanometer-scale objects. These objects include carbon nanotubes, metal and semiconductor nanowires, clusters, and even biological molecules.
Robert Corn (rcorn@uci.edu)
Chemistry
Array fabrication chemistry strategies for oligonucleotides (both DNA and RNA), polypeptides, proteins, and carbohydrates at chemically modified gold surfaces Polarization Modulation FTIR Reflection-Absorption Spectroscopy (PM-FTIRRAS)
Nancy DaSilva (ndasilva@uci.edu)
Chemical Engineering and Materials Science
Molecular biotechnology: cloned gene expression, gene amplification and integration, metabolic engineering, and protein secretion; host/vector design, optimization of fermentation strategies, and mathematical modeling; microbial degradation of toxic substances.
Michael Dennin (mdennin@uci.edu)
Physics
Nonequilibrium dynamics in electroconvection in nematic liquid crystals and Langmuir monolayers
Peter Donovan (pdonovan@uci.edu)
Developmental & Cell Biology; Sue Bill Gross Stem Cell Research Center
Stem cell research
James Earthman (earthman@uci.edu)
Chemical Engineering and Materials Science
High temperature fracture mechanisms; cavitation processes in superplastic materials; numerical modeling of deformation and damage processes; mechanical behavior and damage mechanisms in biomedical materials; corrosion prevention using regenerative biofilms; novel damage monitoring techniques; and automated materials testing and analysis. D2
Gregory Evans (gevans@uci.edu)
Department of Surgery
Plastic Surgery
Lisa Flanagan (lflanaga@uci.edu)
Department of Pathology and Laboratory Medicine
Her lab is interested in the mechanisms that control the generation of functional neurons from stem cells. Using mouse and human neural stem cells, they have begun to identify genetic and environmental cues that regulate the proliferation (green nestin-positive cells in picture) and neuronal differentiation (red TuJ1-positive neuron in picture) of these cells. They are also exploring three-dimensional biomaterials that would be suitable as transplantation scaffolds for both neural and human embryonic stem cells. In a collaboration with Drs. Noo Li Jeon (Biomedical Engineering), Abe Lee (Biomedical Engineering), and Edwin Monuki (Pathology), they are using engineered microfluidic platforms to prospectively sort stem cells and expose them to continuous gradients of soluble factors in order to determine optimal conditions to specify differentiation.
Maria Feng (mfeng@uci.edu)
Civil and Environmental Engineering
Structural engineering: experimental mechanics, structural analysis and design, structural dynamics, and vibration control.
Steven George (scgeorge@uci.edu)
Biomedical Engineering
Characterization of endogenous and exogenous nitric oxide exchange in the lungs; wound healing and extracellular matric remodeling in the lungs; drug delivery of nitric oxide, nitric oxide donors and peptides; and cytokine-induced production of nitrous oxide in the lungs, particularly in response to exercise.
Enrico Gratton (egratton@uci.edu)
Director of Laboratory for Fluorescence Dynamics; Biomedical Engineering
Director of Laboratory of Fluorescence Dynamics
Steven Gross (sgross@uci.edu)
Developmental & Cell Biology
Molecular motors – microtubules
Zhibin Guan (zguan@uci.edu)
Chemistry
Organic Polymer Chemistry, Biommetic Materials and Biomaterials, Polymerization Catalysis
G. Wesley Hatfield (wes.hatfield@uci.edu)
Director, IGB Computational Biology Research Laboratory (CBRL); Microbiology & Molecular Genetics; Chemical Engineering & Materials Science
Molecular mechanisms of biological control systems; global gene expression; genomics; bioinformatics; computational biology
Wilson Ho (wilsonho@uci.edu)
Physics and Astronomy; Chemistry
Nanoscience: Single Molecule Imaging, Manipulation, Spectroscopy, and Chemistry; Nanomagnetism; Variable, Low Temperature Scanning Tunneling Microscopes in Ultrahigh Vacuum; Novel Instrumentation and Experimental Methods
Lan Huang (lanhuang@uci.edu)
Physiology & Biophysics; Developmental & Cell Biology
Biological mass spectrometry/proteomics, ubiquitin-proteasome degradation pathways, protein complexes, posttranslational modifications, protein-protein interaction
Chris Hughes (cchughes@uci.edu)
Molecular Biology & Biochemistry
Endothelial Cell Interactions with the Immune System; Angiogenesis
Elliot Hui (eehui@uci.edu)
Biomedical Engineering
Biological Microtechnology: spatial cell biology, microscale tissue engineering, global health diagnostics, microfluidic computing
Hans Keirstead (hansk@uci.edu)
Anatomy & Neurobiology, and Sue and Bill Gross Stem Cell Research Center
Stem Cell research: Development of strategies to limit degeneration and enhance regeneration after spinal cord injury, with emphasis on human embryonic stem cells
Janos Lanyi (jklanyi@uci.edu)
Physiology and Biophysics
Bacteriorhodopsin, spectroscopy, protein crystallography
John LaRue (jclarue@uci.edu)
Mechanical and Aerospace Engineering
Design and development of micro-electro-mechanical systems (MEMS), fluid mechanics, heat transfer and turbulence, and other areas that bridge those fields.
Matt Law (matt.law@uci.edu)
Chemistry
nanoscale materials and devices, solar energy conversion .
Abraham Lee (aplee@uci.edu)
Director of Micro/Nano Fluidics Fundamental Focus Center (MF3), Biomedical Engineering
Integrated micro- and nano-fluidic chip processors for the manipulation and self-assembly of biomolecules and other synthesized nanoparticles.
Chin Lee (cclee@uci.edu)
Electrical and Computer Engineering
Electronic packaging, thermal management, integrated optics.
Eva Lee (elee@uci.edu)
Department of Biological Chemistry
Cell cycle and molecular genetics studies of breast cancer
Henry Lee (hplee@uci.edu)
Electrical and Computer Engineering
Fiber-optics and compound semiconductor technology. In the fiber-optic area, the research is aimed at advancing an all-in-the-fiber platform for telecommunication and sensor networks.
GP Li (gpli@uci.edu)
Director, Integrated Nanosystems Research Facility;Electrical Engineering and Computer Science; Biomedical Engineering
High-speed semiconductor technology, optoelectronic devices, integrated circuit fabrication and testing. Design and fabrication of microelectromechanical systems.
Marc Madou (mmadou@uci.edu)
Mechanical and Aerospace Engineering; Biomedical Engineering; Chemical Engineering and Materials Science
Miniaturization science (MEMS and NEMS) with emphasis on chemical and biological applications. Current projects include polymer actuators (for drug delivery), C-MEMS and CD based fluidics. Besides miniaturization techniques and materials choices, scaling laws are considered.
Alexander McPherson (amcphers@uci.edu)
Molecular Biology & Biochemistry
Research on macromolecular crystal growth; X-ray and diffraction analysis of protein, nucleic acid and virus crystals; Atomic Force Microscopy studies of biological structures
Dan Mercola (dmercola@uci.edu)
Pathology & Laboratory Medicine
Translational Cancer Biology
Ed Monuki (emonuki@uci.edu)
Pathology
The goal of Professor Monuki’s laboratory is to understand how the cerebral cortex and its NSCs develop, then apply this information to human disorders and NSC culture strategies for potential cell-based therapies
Daniel Mumm (mumm@uci.edu)
Chemical Engineering and Materials Science
Advanced materials and structures, micro-structural characterization, thermo-mechanical behavior.
Edward Nelson (enelson@uci.edu)
Molecular Biology and Biochemistry
Tumor Immunology, Dendritic Cell Biology, Immunotherapeutics & Genetic Vaccines, Viral vectors – alphavirus
Richard Nelson (rnelson@uci.edu)
Electrical and Computer Engineering
Sensors, microelectronics, photonics, medical imaging. Phototherapy and biomedical device development.
James Nowick (jsnowick@uci.edu)
Chemistry
Organic and Bioorganic Chemistry, Chemical Biology, Biomolecular Nanotechnology
Reginald Penner (rmpenner@uci.edu)
Chemistry
Development of new synthetic methods for preparing nanomaterials that have unique and useful properties for chemical sensing, and for other applications. The emphasis is on electronic materials including metals, metal oxides, semiconductors, thermoelectric materials, and electronically conductive polymers; Characterization capabilities includeTEM, SAED, SEM, EDX, XPS, and powder XRD
Thomas Poulos (poulos@uci.edu)
Molecular Biology & Biochemistry
Protein crystallography, protein enginering, heme enzyme structure and function.
Andrew Putnam (aputnam@uci.edu)
Chemical Engineering & Materials Science
Cell and tissue engineering, cellular signal transduction, biomaterials, integrins/cytoskeleton.
Regina Ragan (rragan@uci.edu)
Chemical Engineering and Materials Science
Self-assembly of hybrid organic/inorganic nanostructures for nanoscale electronic and sensing applications; correlating electron transport and optical properties with atomic and molecular structure.
Thorsten Ritz (tritz@uci.edu)
Physics
Physical modeling of structurally known photosynthetic systems and the study of model systems for magnetoreception in animals.
Ken Shea (kjshea@uci.edu)
Chemistry; Chemical Engineering
Organic Synthesis; Molecular Imprinting; Polymer and Material Synthesis
Andrei Shkel (ashkel@uci.edu)
Mechanical and Aerospace Engineering
Design and advanced control of micro- electromechanical systems (MEMS); High-precision micro-machined gyroscopes; MEMS-enhanced optical systems, tools, and prosthetic appliances; Electro-mechanical and machine-information systems integration.
Zuzanna Siwy (zsiwy@uci.edu)
Physics
Experimental Biophysics, Condensed Matter Physics
Eric Stanbridge (ejstanbr@uci.edu)
Microbiology & Molecular Genetics
Tumor suppressor genes and oncogenes in human cancer
Daniel Stokols (dstokols@uci.edu)
School of Social Ecology
Social factors that influence the success of transdisciplinary research and training programs
William Tang (william.c.tang@uci.edu)
Biomedical Engineering and Electrical Engineering
Microscale and nanoscale engineering for information technology and biomedical sciences: Applications in
Bruce Tromberg (bjtrombe@uci.edu)
Director of Beckman Laser Institute and Medical Clinic; Biomedical Engineering
Development and application of novel optical techniques for non-invasive monitoring and imaging of physiological processes in tissues and cells.
Chen Tsai (cstsai@uci.edu)
Electrical Engineering & Computer Science
Integrated and fiber optics, devices, and materials, acoustoopics, magnetooptics, acoustic microscopy.
Vasan Venugopalan (vvenugop@uci.edu)
Chemical Engineering & Materials Science; Biomedical Engineering
Laser-induced thermal, mechanical and radiative transport processes for application in medical diagnostics, therapeutics, biotechnology, and micro-electro-mechanical systems (MEMS).
Szu Wang (wangsw@uci.edu)
Chemical Engineering & Materials Science; Biomedical Engineering
Fabrication of inorganic nanoarrays using biological templates; design of nanoscale protein complexes for molecular transport of molecules; development of novel biopolymers for drug delivery. These studies have relevance in technological areas that include pharmaceutics, tissue engineering, biosensors, and electronic and optical devices.
Ping Wang (phwang@uci.edu)
School of Medicine — Endocrinology
Insulin-like growth factor, Heart, Diabetes, Diabetes Complications
Hemantha (Kumar) Wickramasinghe (hkwick@uci.edu)
Electrical Engineering & Computer Science
Development and applications of microscopes and instruments for nano-scale characterizations vibrating mode atomic force microscope (AFM), the magnetic force microscope, the electrostatic force microscope, the Kelvin probe force microscope, the scanning thermal microscope, and the apertureless near-field optical microscope.
Brian Wong (bjwong@uci.edu)
Biomedical Engineering
Otolaryngology, Laser therapeutics of cartilage and fat
Albert Yee (afyee@uci.edu)
Chemical Engineering and Materials Science
Physical and mechanical properties of polymers and soft materials, particularly on how they impact nanotechnology.
Tau-Mu Yi (tmy@uci.edu)
Developmental & Cell Biology
G-protein signaling; Systems Biology
Claire Yu (cyu@uci.edu)
Physics
Condensed matter physics and biophysics
Fan-Gan Zeng (fzeng@uci.edu)
Biomedical Engineering
Auditory perception, computational neuroscience, speech processing, cochlear, vestibular implants
Albert Zlotnik (azlotnik@uci.edu)
Physiology and Biophysics
Chemokine biology and cancer; molecular characterization of human diseases using genomic-microarray technologies; chemokine research including the role of chemokines in cancer metastasis, use of genearryas for the molecular characterization of human diseases including hepatitis C, idiopathic pulmonary fibrosis, endometriosis, adenomyosis and many cancers; construction of a database of gene expression of more than 85 sites of the human body.